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Role of Reduced Sarco-Endoplasmic Reticulum Ca(2+)-ATPase Function on Sarcoplasmic Reticulum Ca(2+) Alternans in the Intact Rabbit Heart
Sarcoplasmic reticulum (SR) Ca(2+) cycling is tightly regulated by ryanodine receptor (RyR) Ca(2+) release and sarco-endoplasmic reticulum Ca(2+)-ATPase (SERCA) Ca(2+) uptake during each excitation–contraction coupling cycle. We previously showed that RyR refractoriness plays a key role in the onset...
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| Publicado no: | Front Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8144333/ https://ncbi.nlm.nih.gov/pubmed/34045974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.656516 |
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