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Refractoriness of sarcoplasmic reticulum Ca(2+) release determines Ca(2+) alternans in atrial myocytes

Cardiac alternans is a recognized risk factor for cardiac arrhythmia and sudden cardiac death. At the cellular level, Ca(2+) alternans appears as cytosolic Ca(2+) transients of alternating amplitude at regular beating frequency. Cardiac alternans is a multifactorial process but has been linked to di...

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Detalhes bibliográficos
Main Authors: Shkryl, Vyacheslav M., Maxwell, Joshua T., Domeier, Timothy L., Blatter, Lothar A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378301/
https://ncbi.nlm.nih.gov/pubmed/22467301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00079.2012
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