HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism

SUMMARY: The RNA-binding proteins Rbfox1/2/3 regulate alternative splicing in the nervous system, and disruption of Rbfox1 has been implicated in autism. However, comprehensive identification of functional Rbfox targets has been challenging. Here we performed HITS-CLIP for all three Rbfox family mem...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Weyn-Vanhentenryck, Sebastien M, Mele, Aldo, Yan, Qinghong, Sun, Shuying, Farny, Natalie, Zhang, Zuo, Xue, Chenghai, Herre, Margaret, Silver, Pamela A, Zhang, Michael Q, Krainer, Adrian R, Darnell, Robert B, Zhang, Chaolin
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992522/
https://ncbi.nlm.nih.gov/pubmed/24613350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.005
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki