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Rbfox splicing factors promote neuronal maturation and axon initial segment assembly

Neuronal maturation requires dramatic morphological and functional changes, but the molecular mechanisms governing this process are not well understood. Here, we studied the role of Rbfox1-3 proteins, a family of tissue-specific splicing regulators mutated in multiple neurodevelopmental disorders. W...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Jacko, Martin, Weyn-Vanhentenryck, Sebastien M., Smerdon, John W., Yan, Rui, Feng, Huijuan, Williams, Damian J., Pai, Joy, Xu, Ke, Wichterle, Hynek, Zhang, Chaolin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823762/
https://ncbi.nlm.nih.gov/pubmed/29398366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.020
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