Rbfox splicing factors promote neuronal maturation and axon initial segment assembly

Neuronal maturation requires dramatic morphological and functional changes, but the molecular mechanisms governing this process are not well understood. Here, we studied the role of Rbfox1-3 proteins, a family of tissue-specific splicing regulators mutated in multiple neurodevelopmental disorders. W...

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Publicat a:Neuron
Autors principals: Jacko, Martin, Weyn-Vanhentenryck, Sebastien M., Smerdon, John W., Yan, Rui, Feng, Huijuan, Williams, Damian J., Pai, Joy, Xu, Ke, Wichterle, Hynek, Zhang, Chaolin
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823762/
https://ncbi.nlm.nih.gov/pubmed/29398366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.020
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