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The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

The Rbfox proteins (Rbfox1, Rbfox2, and Rbfox3) regulate the alternative splicing of many important neuronal transcripts and have been implicated in a variety of neurological disorders. However, their roles in brain development and function are not well understood, in part due to redundancy in their...

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Hlavní autoři: Gehman, Lauren T., Meera, Pratap, Stoilov, Peter, Shiue, Lily, O'Brien, Janelle E., Meisler, Miriam H., Ares, Manuel, Otis, Thomas S., Black, Douglas L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305983/
https://ncbi.nlm.nih.gov/pubmed/22357600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.182477.111
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