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RBFOX PROTEINS REGULATE ALTERNATIVE SPLICING OF NEURONAL SODIUM CHANNEL SCN8A
The SCN8A gene encodes the voltage-gated sodium channel Na(v)1.6, a major channel in neurons of the CNS and PNS. SCN8A contains two alternative exons, 18N and 18A, that exhibit tissue specific splicing. In brain, the major SCN8A transcript contains exon 18A and encodes the full-length sodium channel...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3278527/ https://ncbi.nlm.nih.gov/pubmed/22044765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2011.10.005 |
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