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The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

The Rbfox family of RNA binding proteins regulates alternative splicing of many important neuronal transcripts but their role in neuronal physiology is not clear(1). We show here that central nervous system (CNS)-specific deletion of the Rbfox1 gene results in heightened susceptibility to spontaneou...

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Autores principales: Gehman, Lauren T., Stoilov, Peter, Maguire, Jamie, Damianov, Andrey, Lin, Chia-Ho, Shiue, Lily, Ares, Manuel, Mody, Istvan, Black, Douglas L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125461/
https://ncbi.nlm.nih.gov/pubmed/21623373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.841
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