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The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

The Rbfox family of RNA binding proteins regulates alternative splicing of many important neuronal transcripts but their role in neuronal physiology is not clear(1). We show here that central nervous system (CNS)-specific deletion of the Rbfox1 gene results in heightened susceptibility to spontaneou...

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Detalhes bibliográficos
Main Authors: Gehman, Lauren T., Stoilov, Peter, Maguire, Jamie, Damianov, Andrey, Lin, Chia-Ho, Shiue, Lily, Ares, Manuel, Mody, Istvan, Black, Douglas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125461/
https://ncbi.nlm.nih.gov/pubmed/21623373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.841
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