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Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2

RBFOX1 and RBFOX2 are alternative splicing factors that are predominantly expressed in the brain and skeletal muscle. They specifically bind the RNA element UGCAUG, and regulate alternative splicing positively or negatively in a position-dependent manner. The molecular basis for the position depende...

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Hlavní autoři: Sun, Shuying, Zhang, Zuo, Fregoso, Oliver, Krainer, Adrian R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264914/
https://ncbi.nlm.nih.gov/pubmed/22184459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030486.111
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