Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis

Identifying sites where RNA binding proteins (RNABPs) interact with target RNAs opens the door to understanding the vast complexity of RNA regulation. UV-crosslinking and immunoprecipitation (CLIP) is a transformative technology in which RNAs purified from in vivo cross-linked RNA-protein complexes...

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Bibliografiske detaljer
Main Authors: Moore, Michael, Zhang, Chaolin, Gantman, Emily Conn, Mele, Aldo, Darnell, Jennifer C., Darnell, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156013/
https://ncbi.nlm.nih.gov/pubmed/24407355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.012
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