PEGylation of brain-derived neurotrophic factor for preserved biological activity and enhanced spinal cord distribution

Brain-derived neurotrophic factor (BDNF) was covalently attached to polyethylene glycol (PEG) in order to enhance delivery to the spinal cord via the cerebrospinal fluid (intrathecal administration). By varying reaction conditions, mixtures of BDNF covalently attached to one (primary), two (secondar...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Soderquist, Ryan G., Milligan, Erin D., Sloane, Evan M., Harrison, Jacqueline A., Douvas, Klarika K., Potter, Joseph M., Hughes, Travis S., Chavez, Raymond A., Johnson, Kirk, Watkins, Linda R., Mahoney, Melissa J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990442/
https://ncbi.nlm.nih.gov/pubmed/19048635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32254
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים