Intrathecal Injection of Naked Plasmid DNA Provides Long-term Expression of Secreted Proteins

Therapeutic benefit has been reported to result from intrathecal (i.t.) injection of transgene vectors, including naked DNA. However, most studies using naked DNA have measured only the transgene expression of intracellular proteins. Here we demonstrate that i.t. injection of naked DNA can result in...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Hughes, Travis S, Langer, Stephen J, Johnson, Kirk W, Chavez, Raymond A, Watkins, Linda R, Milligan, Erin D, Leinwand, Leslie A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2008
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834984/
https://ncbi.nlm.nih.gov/pubmed/18941439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.230
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk