Long-Term Reduction of Cocaine Self-Administration in Rats Treated with Adenoviral Vector-Delivered Cocaine Hydrolase: Evidence for Enzymatic Activity

A new pharmacokinetic approach treating cocaine addiction involves rapidly metabolizing cocaine before it reaches brain reward centers using mutated human butyrylcholinesterase (BChE) or cocaine hydrolase (CocH). Recent work has shown that helper-dependent adenoviral (hdAD) vector-mediated plasma Co...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zlebnik, Natalie E, Brimijoin, Stephen, Gao, Yang, Saykao, Amy T, Parks, Robin J, Carroll, Marilyn E
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988560/
https://ncbi.nlm.nih.gov/pubmed/24407266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares