Carregant...

Long-Term Blockade of Cocaine Self-Administration and Locomotor Activation in Rats by an Adenoviral Vector–Delivered Cocaine Hydrolase

A promising approach in treating cocaine abuse is to metabolize cocaine in the blood using a mutated butyrylcholinesterase (BChE) that functions as a cocaine hydrolase (CocH). In rats, a helper-dependent adenoviral (hdAD) vector–mediated delivery of CocH abolished ongoing cocaine use and cocaine-pri...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Pharmacol Exp Ther
Autors principals: Smethells, John R., Swalve, Natashia, Brimijoin, Stephen, Gao, Yang, Parks, Robin J., Greer, Adam, Carroll, Marilyn E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851322/
https://ncbi.nlm.nih.gov/pubmed/26968195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232504
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!