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Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats

RATIONALE AND OBJECTIVES: Previously, Albu-CocH, a cocaine hydrolase derived from human butyrylcholinesterase, blocked cocaine-induced reinstatement of drug seeking in rats. In the present study, rats were treated with Albu-CocH while self-administering cocaine under a progressive ratio (PR) schedul...

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Bibliografski detalji
Glavni autori: Carroll, Marilyn E., Gao, Yang, Brimijoin, Stephen, Anker, Justin J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631565/
https://ncbi.nlm.nih.gov/pubmed/20972552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2040-3
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