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Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats
RATIONALE AND OBJECTIVES: Previously, Albu-CocH, a cocaine hydrolase derived from human butyrylcholinesterase, blocked cocaine-induced reinstatement of drug seeking in rats. In the present study, rats were treated with Albu-CocH while self-administering cocaine under a progressive ratio (PR) schedul...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631565/ https://ncbi.nlm.nih.gov/pubmed/20972552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-2040-3 |
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