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Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis

Focal segmental glomerular sclerosis (FSGS) is a primary kidney disease that is commonly associated with proteinuria and progressive loss of glomerular function, leading to development of chronic kidney disease (CKD). FSGS is characterized by podocyte injury and depletion and collapse of glomerular...

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Bibliografische gegevens
Hoofdauteurs: Daehn, Ilse, Casalena, Gabriella, Zhang, Taoran, Shi, Shaolin, Fenninger, Franz, Barasch, Nicholas, Yu, Liping, D’Agati, Vivette, Schlondorff, Detlef, Kriz, Wilhelm, Haraldsson, Borje, Bottinger, Erwin P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973074/
https://ncbi.nlm.nih.gov/pubmed/24590287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71195
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