Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis

Focal segmental glomerular sclerosis (FSGS) is a primary kidney disease that is commonly associated with proteinuria and progressive loss of glomerular function, leading to development of chronic kidney disease (CKD). FSGS is characterized by podocyte injury and depletion and collapse of glomerular...

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Bibliographic Details
Main Authors: Daehn, Ilse, Casalena, Gabriella, Zhang, Taoran, Shi, Shaolin, Fenninger, Franz, Barasch, Nicholas, Yu, Liping, D’Agati, Vivette, Schlondorff, Detlef, Kriz, Wilhelm, Haraldsson, Borje, Bottinger, Erwin P.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973074/
https://ncbi.nlm.nih.gov/pubmed/24590287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71195
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