Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis

Focal segmental glomerular sclerosis (FSGS) is a primary kidney disease that is commonly associated with proteinuria and progressive loss of glomerular function, leading to development of chronic kidney disease (CKD). FSGS is characterized by podocyte injury and depletion and collapse of glomerular...

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Autores principales: Daehn, Ilse, Casalena, Gabriella, Zhang, Taoran, Shi, Shaolin, Fenninger, Franz, Barasch, Nicholas, Yu, Liping, D’Agati, Vivette, Schlondorff, Detlef, Kriz, Wilhelm, Haraldsson, Borje, Bottinger, Erwin P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973074/
https://ncbi.nlm.nih.gov/pubmed/24590287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71195
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