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TGFβ-induced actin cytoskeleton rearrangement in podocytes is associated with compensatory adaptation of mitochondrial energy metabolism
BACKGROUND/AIMS: In podocytes, the overexpression of TGFβ ligands and receptors during glomerulosclerosis could be causal for injury induction and perpetuation in glomerular tufts. Mitochondrial dysfunction and oxidative stress are emerging as potential therapeutic targets in glomerular injury and T...
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| Udgivet i: | Nephron |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687741/ https://ncbi.nlm.nih.gov/pubmed/26613578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000442051 |
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