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TGFβ-induced actin cytoskeleton rearrangement in podocytes is associated with compensatory adaptation of mitochondrial energy metabolism

BACKGROUND/AIMS: In podocytes, the overexpression of TGFβ ligands and receptors during glomerulosclerosis could be causal for injury induction and perpetuation in glomerular tufts. Mitochondrial dysfunction and oxidative stress are emerging as potential therapeutic targets in glomerular injury and T...

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Detalhes bibliográficos
Publicado no:Nephron
Main Authors: Casalena, Gabriella, Böttinger, Erwin, Daehn, Ilse
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687741/
https://ncbi.nlm.nih.gov/pubmed/26613578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000442051
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