Glomerular Endothelial Mitochondrial Dysfunction Is Essential and Characteristic of Diabetic Kidney Disease Susceptibility

The molecular signaling mechanisms between glomerular cell types during initiation/progression of diabetic kidney disease (DKD) remain poorly understood. We compared the early transcriptome profile between DKD-resistant C57BL/6J and DKD-susceptible DBA/2J (D2) glomeruli and demonstrated a significan...

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Enregistré dans:
Détails bibliographiques
Publié dans:Diabetes
Auteurs principaux: Qi, Haiying, Casalena, Gabriella, Shi, Shaolin, Yu, Liping, Ebefors, Kerstin, Sun, Yezhou, Zhang, Weijia, D’Agati, Vivette, Schlondorff, Detlef, Haraldsson, Börje, Böttinger, Erwin, Daehn, Ilse
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2017
Sujets:
Complications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319717/
https://ncbi.nlm.nih.gov/pubmed/27899487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0695
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