Epithelial Cell TGFβ Signaling Induces Acute Tubular Injury and Interstitial Inflammation

TGFβ signaling plays a central role in the development of acute and chronic kidney diseases. Previous in vivo studies involved systemic alteration of TGFβ signaling, however, limiting conclusions about the direct role of TGFβ in tubular cell injury. Here, we generated a double transgenic mouse that...

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Detaylı Bibliyografya
Asıl Yazarlar: Gentle, Madeleine E., Shi, Shaolin, Daehn, Ilse, Zhang, Taoran, Qi, Haiying, Yu, Liping, D’Agati, Vivette D., Schlondorff, Detlef O., Bottinger, Erwin P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2013
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636798/
https://ncbi.nlm.nih.gov/pubmed/23539761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012101024
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