Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro

Mitochondrial dysfunction is increasingly recognized as contributing to glomerular diseases, including those secondary to mitochondrial DNA (mtDNA) mutations and deletions. Mitochondria maintain cellular redox and energy homeostasis and are a major source of intracellular reactive oxygen species (RO...

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Main Authors: Casalena, Gabriela, Krick, Stefanie, Daehn, Ilse, Yu, Liping, Ju, Wenjun, Shi, Shaolin, Tsai, Su-yi, D'Agati, Vivette, Lindenmeyer, Maja, Cohen, Clemens D., Schlondorff, Detlef, Bottinger, Erwin P.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042102/
https://ncbi.nlm.nih.gov/pubmed/24598802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00608.2013
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