Mpv17 in mitochondria protects podocytes against mitochondrial dysfunction and apoptosis in vivo and in vitro

Mitochondrial dysfunction is increasingly recognized as contributing to glomerular diseases, including those secondary to mitochondrial DNA (mtDNA) mutations and deletions. Mitochondria maintain cellular redox and energy homeostasis and are a major source of intracellular reactive oxygen species (RO...

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Autors principals: Casalena, Gabriela, Krick, Stefanie, Daehn, Ilse, Yu, Liping, Ju, Wenjun, Shi, Shaolin, Tsai, Su-yi, D'Agati, Vivette, Lindenmeyer, Maja, Cohen, Clemens D., Schlondorff, Detlef, Bottinger, Erwin P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042102/
https://ncbi.nlm.nih.gov/pubmed/24598802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00608.2013
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