Epithelial Cell TGFβ Signaling Induces Acute Tubular Injury and Interstitial Inflammation

TGFβ signaling plays a central role in the development of acute and chronic kidney diseases. Previous in vivo studies involved systemic alteration of TGFβ signaling, however, limiting conclusions about the direct role of TGFβ in tubular cell injury. Here, we generated a double transgenic mouse that...

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Bibliografiske detaljer
Main Authors: Gentle, Madeleine E., Shi, Shaolin, Daehn, Ilse, Zhang, Taoran, Qi, Haiying, Yu, Liping, D’Agati, Vivette D., Schlondorff, Detlef O., Bottinger, Erwin P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2013
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636798/
https://ncbi.nlm.nih.gov/pubmed/23539761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012101024
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