Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

Dicer is an enzyme that generates microRNA (miRNA), which are small, noncoding RNA that function as important regulators of gene and protein expression. For exploration of the functional roles of miRNA in glomerular biology, Dicer was inactivated selectively in mouse podocytes. Mutant mice developed...

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Main Authors: Shi, Shaolin, Yu, Liping, Chiu, Celine, Sun, Yezhou, Chen, Jin, Khitrov, Greg, Merkenschlager, Matthias, Holzman, Lawrence B., Zhang, Weijia, Mundel, Peter, Bottinger, Erwin P.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2008
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573016/
https://ncbi.nlm.nih.gov/pubmed/18776119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008030312
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