Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

Cationic antimicrobial peptides (CAPs) such as defensins are ubiquitously found innate immune molecules that often exhibit broad activity against microbial pathogens and mammalian tumor cells. Many CAPs act at the plasma membrane of cells leading to membrane destabilization and permeabilization. In...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Poon, Ivan KH, Baxter, Amy A, Lay, Fung T, Mills, Grant D, Adda, Christopher G, Payne, Jennifer AE, Phan, Thanh Kha, Ryan, Gemma F, White, Julie A, Veneer, Prem K, van der Weerden, Nicole L, Anderson, Marilyn A, Kvansakul, Marc, Hulett, Mark D
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968744/
https://ncbi.nlm.nih.gov/pubmed/24692446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01808
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados