The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process

Por Baxter, Amy A, Poon, Ivan KH, Hulett, Mark D
Publicado no Cell Death Discov (2017)

The lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells

Por Baxter, Amy A, Poon, Ivan KH, Hulett, Mark D
Publicado no Cell Death Dis (2017)

Crystallization and preliminary X-ray crystallographic analysis of the plant defensin NaD1

Por Lay, Fung T., Mills, Grant D., Hulett, Mark D., Kvansakul, Marc
Publicado em 2011

Recombinant expression and purification of the tomato defensin TPP3 and its preliminary X-ray crystallographic analysis

Por Lay, Fung T., Veneer, Prem K., Hulett, Mark D., Kvansakul, Marc
Publicado em 2012

Soluble Heparan Sulfate Fragments Generated by Heparanase Trigger the Release of Pro-Inflammatory Cytokines through TLR-4

Por Goodall, Katharine J., Poon, Ivan K. H., Phipps, Simon, Hulett, Mark D.
Publicado em 2014

Functional Regulation of the Plasma Protein Histidine-Rich Glycoprotein by Zn(2+) in Settings of Tissue Injury

Por Priebatsch, Kristin M., Kvansakul, Marc, Poon, Ivan K. H., Hulett, Mark D.
Publicado no Biomolecules (2017)

Structural and Functional Insight into Canarypox Virus CNP058 Mediated Regulation of Apoptosis

Por Anasir, Mohd Ishtiaq, Baxter, Amy A., Poon, Ivan K. H., Hulett, Mark D., Kvansakul, Marc
Publicado no Viruses (2017)

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P(2) to mediate tumour cell permeabilisation

Por Phan, Thanh Kha, Lay, Fung T., Poon, Ivan K.H., Hinds, Mark G., Kvansakul, Marc, Hulett, Mark D.
Publicado no Oncotarget (2015)

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer

Por Quah, Ben J. C., Barlow, Vaughan P., McPhun, Virginia, Matthaei, Klaus I., Hulett, Mark D., Parish, Christopher R.
Publicado em 2008

Determining the contents and cell origins of apoptotic bodies by flow cytometry

Por Jiang, Lanzhou, Paone, Stephanie, Caruso, Sarah, Atkin-Smith, Georgia K., Phan, Thanh Kha, Hulett, Mark D., Poon, Ivan K. H.
Publicado no Sci Rep (2017)

Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin–lipid oligomeric assemblies and membrane permeabilization

Por Kvansakul, Marc, Lay, Fung T., Adda, Christopher G., Veneer, Prem K., Baxter, Amy A., Phan, Thanh Kha, Poon, Ivan K. H., Hulett, Mark D.
Publicado no Proc Natl Acad Sci U S A (2016)

Isolation of cell type-specific apoptotic bodies by fluorescence-activated cell sorting

Por Atkin-Smith, Georgia K., Paone, Stephanie, Zanker, Damien J., Duan, Mubing, Phan, Than K., Chen, Weisan, Hulett, Mark D., Poon, Ivan K. H.
Publicado no Sci Rep (2017)

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure

Por Atkin-Smith, Georgia K., Tixeira, Rochelle, Paone, Stephanie, Mathivanan, Suresh, Collins, Christine, Liem, Michael, Goodall, Katharine J., Ravichandran, Kodi S., Hulett, Mark D., Poon, Ivan K.H.
Publicado no Nat Commun (2015)

The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis

Por Baxter, Amy A., Richter, Viviane, Lay, Fung T., Poon, Ivan K. H., Adda, Christopher G., Veneer, Prem K., Phan, Thanh Kha, Bleackley, Mark R., Anderson, Marilyn A., Kvansakul, Marc, Hulett, Mark D.
Publicado no Mol Cell Biol (2015)

Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity

Por Lay, Fung T., Mills, Grant D., Poon, Ivan K. H., Cowieson, Nathan P., Kirby, Nigel, Baxter, Amy A., van der Weerden, Nicole L., Dogovski, Con, Perugini, Matthew A., Anderson, Marilyn A., Kvansakul, Marc, Hulett, Mark D.
Publicado em 2012

Nicotiana alata Defensin Chimeras Reveal Differences in the Mechanism of Fungal and Tumor Cell Killing and an Enhanced Antifungal Variant

Por Bleackley, Mark R., Payne, Jennifer A. E., Hayes, Brigitte M. E., Durek, Thomas, Craik, David J., Shafee, Thomas M. A., Poon, Ivan K. H., Hulett, Mark D., van der Weerden, Nicole L., Anderson, Marilyn A.
Publicado no Antimicrob Agents Chemother (2016)

The endoglycosidase heparanase enters the nucleus of T lymphocytes and modulates H3 methylation at actively transcribed genes via the interplay with key chromatin modifying enzymes

Por He, Yi Qing, Sutcliffe, Elissa L., Bunting, Karen L., Li, Jasmine, Goodall, Katharine J., Poon, Ivan K.A., Hulett, Mark D., Freeman, Craig, Zafar, Anjum, McInnes, Russell L., Taya, Toshiki, Parish, Christopher R., Rao, Sudha
Publicado em 2012

NK cell heparanase controls tumor invasion and immune surveillance

Por Putz, Eva M., Mayfosh, Alyce J., Kos, Kevin, Barkauskas, Deborah S., Nakamura, Kyohei, Town, Liam, Goodall, Katharine J., Yee, Dean Y., Poon, Ivan K.H., Baschuk, Nikola, Souza-Fonseca-Guimaraes, Fernando, Hulett, Mark D., Smyth, Mark J.
Publicado no J Clin Invest (2017)

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

Por Poon, Ivan KH, Baxter, Amy A, Lay, Fung T, Mills, Grant D, Adda, Christopher G, Payne, Jennifer AE, Phan, Thanh Kha, Ryan, Gemma F, White, Julie A, Veneer, Prem K, van der Weerden, Nicole L, Anderson, Marilyn A, Kvansakul, Marc, Hulett, Mark D
Publicado em 2014