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The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis

Defensins are a class of ubiquitously expressed cationic antimicrobial peptides (CAPs) that play an important role in innate defense. Plant defensins are active against a broad range of microbial pathogens and act via multiple mechanisms, including cell membrane permeabilization. The cytolytic activ...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Baxter, Amy A., Richter, Viviane, Lay, Fung T., Poon, Ivan K. H., Adda, Christopher G., Veneer, Prem K., Phan, Thanh Kha, Bleackley, Mark R., Anderson, Marilyn A., Kvansakul, Marc, Hulett, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420927/
https://ncbi.nlm.nih.gov/pubmed/25802281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00282-15
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