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Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate–mediated membrane permeabilization
Human defensins belong to a subfamily of the cationic antimicrobial peptides and act as a first line of defense against invading microbes. Their often broad-spectrum antimicrobial and antitumor activities make them attractive for therapeutic development; however, their precise molecular mechanism(s)...
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| Izdano u: | Sci Adv |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Association for the Advancement of Science
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6059731/ https://ncbi.nlm.nih.gov/pubmed/30050988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat0979 |
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