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Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate–mediated membrane permeabilization

Human defensins belong to a subfamily of the cationic antimicrobial peptides and act as a first line of defense against invading microbes. Their often broad-spectrum antimicrobial and antitumor activities make them attractive for therapeutic development; however, their precise molecular mechanism(s)...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Järvå, Michael, Phan, Thanh Kha, Lay, Fung T., Caria, Sofia, Kvansakul, Marc, Hulett, Mark D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059731/
https://ncbi.nlm.nih.gov/pubmed/30050988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat0979
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