X-ray structure of a carpet-like antimicrobial defensin–phospholipid membrane disruption complex

Defensins are cationic antimicrobial peptides expressed throughout the plant and animal kingdoms as a first line of defense against pathogens. Membrane targeting and disruption is a crucial function of many defensins, however the precise mechanism remains unclear. Certain plant defensins form dimers...

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Udgivet i:Nat Commun
Main Authors: Järvå, Michael, Lay, Fung T., Phan, Thanh Kha, Humble, Cassandra, Poon, Ivan K. H., Bleackley, Mark R., Anderson, Marilyn A., Hulett, Mark D., Kvansakul, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5958116/
https://ncbi.nlm.nih.gov/pubmed/29773800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04434-y
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