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Importance of the Caspase Cleavage Site in Amyloid-β Protein Precursor

Reports from multiple laboratories have now been published analyzing the critical nature of the caspase cleavage site of amyloid-β protein precursor (AβPP) for cell death induction, synaptic loss, hippocampal atrophy, long-term potentiation, memory loss, neophobia, and other aspects of the Alzheimer...

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Autors principals: Bredesen, Dale E., John, Varghese, Galvan, Veronica
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968071/
https://ncbi.nlm.nih.gov/pubmed/20847422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100537
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