लोड हो रहा है...
Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation
The shelterin complex plays dual functions in telomere homeostasis by recruiting telomerase and preventing the activation of a DNA damage response at telomeric ends. Somatic stem cells require telomerase activity, as evidenced by progressive stem cell loss leading to bone marrow failure in hereditar...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Clinical Investigation
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967656/ https://ncbi.nlm.nih.gov/pubmed/24316971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67871 |
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