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Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons

Phytochemicals are a rich source of anticancer drugs and chemopreventive agents. Several of these chemicals appear to exert at least some of their effects through interactions with topoisomerase II, an essential enzyme that regulates DNA supercoiling and removes knots and tangles from the genome. To...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ketron, Adam C., Osheroff, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963363/
https://ncbi.nlm.nih.gov/pubmed/24678287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11101-013-9291-7
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