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Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons

Phytochemicals are a rich source of anticancer drugs and chemopreventive agents. Several of these chemicals appear to exert at least some of their effects through interactions with topoisomerase II, an essential enzyme that regulates DNA supercoiling and removes knots and tangles from the genome. To...

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Detalhes bibliográficos
Main Authors: Ketron, Adam C., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963363/
https://ncbi.nlm.nih.gov/pubmed/24678287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11101-013-9291-7
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