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Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons

Phytochemicals are a rich source of anticancer drugs and chemopreventive agents. Several of these chemicals appear to exert at least some of their effects through interactions with topoisomerase II, an essential enzyme that regulates DNA supercoiling and removes knots and tangles from the genome. To...

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Bibliografiske detaljer
Main Authors: Ketron, Adam C., Osheroff, Neil
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963363/
https://ncbi.nlm.nih.gov/pubmed/24678287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11101-013-9291-7
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