High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

N6-methyladenosine (m6A) is the most ubiquitous mRNA base modification, but little is known about its precise location, temporal dynamics, and regulation. Here, we generated genomic maps of m6A sites in meiotic yeast transcripts at nearly single-nucleotide resolution, identifying 1,308 putatively me...

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Hoofdauteurs: Schwartz, Schraga, Agarwala, Sudeep D., Mumbach, Maxwell R., Jovanovic, Marko, Mertins, Philipp, Shishkin, Alexander, Tabach, Yuval, Mikkelsen, Tarjei S, Satija, Rahul, Ruvkun, Gary, Carr, Steven A., Lander, Eric S., Fink, Gerald R., Regev, Aviv
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956118/
https://ncbi.nlm.nih.gov/pubmed/24269006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.047
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