High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

N6-methyladenosine (m6A) is the most ubiquitous mRNA base modification, but little is known about its precise location, temporal dynamics, and regulation. Here, we generated genomic maps of m6A sites in meiotic yeast transcripts at nearly single-nucleotide resolution, identifying 1,308 putatively me...

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Библиографические подробности
Главные авторы: Schwartz, Schraga, Agarwala, Sudeep D., Mumbach, Maxwell R., Jovanovic, Marko, Mertins, Philipp, Shishkin, Alexander, Tabach, Yuval, Mikkelsen, Tarjei S, Satija, Rahul, Ruvkun, Gary, Carr, Steven A., Lander, Eric S., Fink, Gerald R., Regev, Aviv
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956118/
https://ncbi.nlm.nih.gov/pubmed/24269006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.047
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