High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

N6-methyladenosine (m6A) is the most ubiquitous mRNA base modification, but little is known about its precise location, temporal dynamics, and regulation. Here, we generated genomic maps of m6A sites in meiotic yeast transcripts at nearly single-nucleotide resolution, identifying 1,308 putatively me...

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Hlavní autoři: Schwartz, Schraga, Agarwala, Sudeep D., Mumbach, Maxwell R., Jovanovic, Marko, Mertins, Philipp, Shishkin, Alexander, Tabach, Yuval, Mikkelsen, Tarjei S, Satija, Rahul, Ruvkun, Gary, Carr, Steven A., Lander, Eric S., Fink, Gerald R., Regev, Aviv
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956118/
https://ncbi.nlm.nih.gov/pubmed/24269006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.047
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