Dynamic profiling of the protein life cycle in response to pathogens

Protein expression is regulated by production and degradation of mRNAs and proteins, but their specific relationships remain unknown. We combine measurements of protein production and degradation and mRNA dynamics to build a quantitative genomic model of the differential regulation of gene expressio...

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Bibliographic Details
Published in:Science
Main Authors: Jovanovic, Marko, Rooney, Michael S., Mertins, Philipp, Przybylski, Dariusz, Chevrier, Nicolas, Satija, Rahul, Rodriguez, Edwin H., Fields, Alexander P., Schwartz, Schraga, Raychowdhury, Raktima, Mumbach, Maxwell R., Eisenhaure, Thomas, Rabani, Michal, Gennert, Dave, Lu, Diana, Delorey, Toni, Weissman, Jonathan S., Carr, Steven A., Hacohen, Nir, Regev, Aviv
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506746/
https://ncbi.nlm.nih.gov/pubmed/25745177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1259038
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