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Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli

Individual genetic variation affects gene expression in response to stimuli, often by influencing complex molecular circuits. Here we combine genomic and intermediate-scale transcriptional profiling with computational methods to identify variants that affect the responsiveness of genes to stimuli (r...

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Bibliografiske detaljer
Main Authors: Gat-Viks, Irit, Chevrier, Nicolas, Wilentzik, Roni, Eisenhaure, Thomas, Raychowdhury, Raktima, Steuerman, Yael, Shalek, Alex, Hacohen, Nir, Amit, Ido, Regev, Aviv
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622156/
https://ncbi.nlm.nih.gov/pubmed/23503680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2519
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