High resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies

Cells control dynamic transitions in transcript levels by regulating transcription, processing and/or degradation through an integrated regulatory strategy. Here, we combine RNA metabolic labeling, rRNA-depleted RNA-seq, and DRiLL, a novel computational framework, to quantify the level, editing site...

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Pubblicato in:Cell
Autori principali: Rabani, Michal, Raychowdhury, Raktima, Jovanovic, Marko, Rooney, Michael, Stumpo, Deborah J., Hacohen, Nir, Schier, Alexander F., Blackshear, Perry J., Friedman, Nir, Amit, Ido, Regev, Aviv
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272607/
https://ncbi.nlm.nih.gov/pubmed/25497548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.015
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