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High resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies
Cells control dynamic transitions in transcript levels by regulating transcription, processing and/or degradation through an integrated regulatory strategy. Here, we combine RNA metabolic labeling, rRNA-depleted RNA-seq, and DRiLL, a novel computational framework, to quantify the level, editing site...
Gespeichert in:
Veröffentlicht in: | Cell |
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Hauptverfasser: | , , , , , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272607/ https://ncbi.nlm.nih.gov/pubmed/25497548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.015 |
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