Transcriptome-wide mapping reveals widespread dynamic regulated pseudouridylation of ncRNA and mRNA

Pseudouridine is the most abundant RNA modification, yet except for a few well-studied cases, little is known about the modified positions and their function(s). Here, we develop Ψ-seq for transcriptome-wide quantitative mapping of pseudouridine. We validate Ψ-seq with spike-ins and de novo identifi...

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Hauptverfasser: Schwartz, Schraga, Bernstein, Douglas A., Mumbach, Maxwell R., Jovanovic, Marko, Herbst, Rebecca H., León-Ricardo, Brian X., Engreitz, Jesse M., Guttman, Mitchell, Satija, Rahul, Lander, Eric S., Fink, Gerald, Regev, Aviv
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180118/
https://ncbi.nlm.nih.gov/pubmed/25219674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.08.028
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