High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

N6-methyladenosine (m6A) is the most ubiquitous mRNA base modification, but little is known about its precise location, temporal dynamics, and regulation. Here, we generated genomic maps of m6A sites in meiotic yeast transcripts at nearly single-nucleotide resolution, identifying 1,308 putatively me...

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Detalhes bibliográficos
Main Authors: Schwartz, Schraga, Agarwala, Sudeep D., Mumbach, Maxwell R., Jovanovic, Marko, Mertins, Philipp, Shishkin, Alexander, Tabach, Yuval, Mikkelsen, Tarjei S, Satija, Rahul, Ruvkun, Gary, Carr, Steven A., Lander, Eric S., Fink, Gerald R., Regev, Aviv
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956118/
https://ncbi.nlm.nih.gov/pubmed/24269006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.047
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