Soluble γ-Secretase Modulators Selectively Inhibit the Production of the 42-Amino Acid Amyloid β Peptide Variant and Augment the Production of Multiple Carboxy-Truncated Amyloid β Species

Lignende værker

• Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease
  af: Kounnas, Maria Z., et al.
  Udgivet: (2010)
• Age-Dependent, Non-Cell-Autonomous Deposition of Amyloid from Synthesis of β-Amyloid by Cells Other Than Excitatory Neurons
  af: Veeraraghavalu, Karthikeyan, et al.
  Udgivet: (2014)
• Identification of NEEP21 as a β-Amyloid Precursor Protein-Interacting Protein In Vivo That Modulates Amyloidogenic Processing In Vitro
  af: Norstrom, Eric M., et al.
  Udgivet: (2010)
• Loss of Function of ATXN1 Increases Amyloid β-Protein Levels by Potentiating β-Secretase Processing of β-Amyloid Precursor Protein
  af: Zhang, Can, et al.
  Udgivet: (2010)
• γ-Secretase modulators reduce endogenous amyloid β(42) levels in human neural progenitor cells without altering neuronal differentiation
  af: D’Avanzo, Carla, et al.
  Udgivet: (2015)