SCF(β-TRCP) targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration

Metastasis suppressor 1 (MTSS1) is an important tumor suppressor protein, and loss of MTSS1 expression has been observed in several types of human cancers. Importantly, decreased MTSS1 expression is associated with more aggressive forms of breast and prostate cancers, and with poor survival rate. Cu...

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Bibliographische Detailangaben
Hauptverfasser: Zhong, Jiateng, Shaik, Shavali, Wan, Lixin, Tron, Adriana E., Wang, Zhiwei, Sun, Liankun, Inuzuka, Hiroyuki, Wei, Wenyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2013
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926831/
https://ncbi.nlm.nih.gov/pubmed/24318128
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