Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8

The roles of microRNAs (miRNAs) and the miRNA processing machinery in the regulation of stem cell biology are not well understood. Here, we show that the p53 family member and p63 isoform, ΔNp63, is a transcriptional activator of a cofactor critical for miRNA processing (DGCR8). This regulation give...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Chakravarti, Deepavali, Su, Xiaohua, Cho, Min Soon, Bui, Ngoc Hoang Bao, Coarfa, Cristian, Venkatanarayan, Avinashnarayan, Benham, Ashley L., Flores González, Ramón E., Alana, Jennifer, Xiao, Weimin, Leung, Marco L., Vin, Harina, Chan, Io Long, Aquino, Arianexys, Müller, Nicole, Wang, Hongran, Cooney, Austin J., Parker-Thornburg, Jan, Tsai, Kenneth Y., Gunaratne, Preethi H., Flores, Elsa R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918754/
https://ncbi.nlm.nih.gov/pubmed/24449888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319743111
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller