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Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8
The roles of microRNAs (miRNAs) and the miRNA processing machinery in the regulation of stem cell biology are not well understood. Here, we show that the p53 family member and p63 isoform, ΔNp63, is a transcriptional activator of a cofactor critical for miRNA processing (DGCR8). This regulation give...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918754/ https://ncbi.nlm.nih.gov/pubmed/24449888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319743111 |
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