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Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73

TP53 is highly mutated in human cancers, thus targeting this tumor suppressor pathway is highly desirable and will impact many cancer patients.(1,2) Therapeutic strategies to reactivate the p53-pathway have been challenging,(3,4) and no effective treatment exists.(5) We utilized the p53-family membe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Cycle
Päätekijät: Venkatanarayan, Avinashnarayan, Raulji, Payal, Norton, William, Flores, Elsa R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825839/
https://ncbi.nlm.nih.gov/pubmed/26652033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121333
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