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Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73
TP53 is highly mutated in human cancers, thus targeting this tumor suppressor pathway is highly desirable and will impact many cancer patients.(1,2) Therapeutic strategies to reactivate the p53-pathway have been challenging,(3,4) and no effective treatment exists.(5) We utilized the p53-family membe...
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| Publicado en: | Cell Cycle |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4825839/ https://ncbi.nlm.nih.gov/pubmed/26652033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1121333 |
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