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p63 and p73, the Ancestors of p53

p73 and p63 are two homologs of the tumor suppressive transcription factor p53. Given the high degree of structural similarity shared by the p53 family members, p73 and p63 can bind and activate transcription from the majority of the p53-responsive promoters. Besides overlapping functions shared wit...

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Detalhes bibliográficos
Main Authors: Dötsch, V., Bernassola, F., Coutandin, D., Candi, E., Melino, G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926756/
https://ncbi.nlm.nih.gov/pubmed/20484388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a004887
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