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p63 steps into the limelight: crucial roles in the suppression of tumorigenesis and metastasis

The role of p63 in cancer has been an area of intense debate and controversy. Is TP63 (which encodes p63) a tumour suppressor gene or an oncogene? This debate is partly due to the complexity of the gene. There are several p63 isoforms — some with tumour suppressive functions and others with oncogeni...

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Detalhes bibliográficos
Main Authors: Su, Xiaohua, Chakravarti, Deepavali, Flores, Elsa R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181578/
https://ncbi.nlm.nih.gov/pubmed/23344544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3446
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