Carregant...
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
Multiple genetic variants of CARD15/NOD2 have been associated with susceptibility to Crohn's disease and Blau syndrome. NOD2 recognizes muramyl dipeptide (MDP) derived from bacterial peptidoglycan (PGN), but the molecular basis of recognition remains elusive. We performed systematic mutational...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC391079/ https://ncbi.nlm.nih.gov/pubmed/15044951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600175 |
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